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Penny Beuning

Associate Professor, Chemistry and Chemical Biology
Affiliated Faculty, Bioengineering
06 Hurtig Hall
360 Huntington Avenue
Boston, MA 02115


2000 Ph.D. University of Minnesota
1994 B.A. Macalester College, St. Paul, Minnesota

Research & Scholarship Interests

Chemical biology and biotechnology
Affiliated With

Department Research Areas

Honors & Awards

  • 2012, American Cancer Society Research Scholar Award
  • 2009, National Science Foundation CAREER Award
  • 2009, Cottrell Scholar Award

Selected Publications

  • P. Nevin, X. Lu, K. Zhang, J.R. Engen, P.J. Beuning, Non-cognate DNA Damage Prevents Formation of Active Conformation of Y-family DNA Polymerases DinB and Pol Kappa, The FEBS Journal, 282, 2015, 2646-2660
  • P. Nevin, V. Kairys, C. Venclovas, J.R. Engen, P.J. Beuning, Conformational Analysis of Processivity Clamps in Solution Demonstrates That Tertiary Structure Does not Correlate with Protein Dynamics, Structure, 22, 2014, 572-581
  • J.N. Ollivierre, J.L. Sikora, P.J. Beuning, Dimer Exchange and Cleavage Specificity of the DNA Damage Response Protein UmuD, Biochimica et Biophysica Acta-Proteins and Proteomics, 1834, 2013, 611-620
  • J.M. Walsh, P.J. Ippoliti, E.A. Ronayne, E. Rozners, P.J. Beuning, Discrimination Against Major Groove Adducts by Y Family Polymerases of the DinB Subfamily, DNA Repair, 12, 2013, 713-722
  • K.R. Chaurasiya, C. Ruslie, M.C. Silva, L. Voortman, P. Nevin, S. Lone, P.J. Beuning, M.C. Williams, Polymerase Manager Protein UmuD Directly Regulates E. coli DNA Polymerase III Binding to ssDNA, Nucleic Acids Research, 41, 2013, 8959-8968

Related News

March 22, 2016

23 COE faculty and affiliates were recipients of FY17 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing over $600K dollars of investment in research.