Samuel Chung

Assistant Professor,  Bioengineering

Contact

Office

  • 617.373.7805

Related Links

Research Focus

Brain cell regeneration, automated microscopy and laser surgery, user-friendly and low-cost fluorescence microscopy

Education

  • PhD,  Applied Physics, Harvard University, 2009
  • S.M., Applied Physics, Harvard University, 2004
  • B.S., Applied Physics, California Institute of Technology, 2000

Research Overview

Brain cell regeneration, automated microscopy and laser surgery, user-friendly and low-cost fluorescence microscopy

Regeneration and Optics Laboratory

The NeuroLab studies neuroregeneration in the roundworm C. elegans. We develop advanced devices and techniques for microscopy and imaging.
NeuroLab

Selected Research Projects

  • Automated microscope platform with improved imaging and accurate neuron reconstruction capabilities for high-throughput studies of neuroregeneration
    • – Principal Investigator, NIH
  • High-Throughput Microscopy Platform for Accelerating Regeneration Neuroscience
    • – Principal Investigator, Northeastern TIER 1
  • Transcriptomic, Genetic, and Optogenetic Analysis of a Novel High-Throughput Model for Lesion-Conditioned Regeneration
    • – Principal Investigator, Morton Cure Paralysis

Selected Publications

  • Grooms, N.W.F., Fitzgerald, M.Q., Zuckerman, B., Ureña, S.E., Weinberger, L.S., and Chung, S.H. (2023). Expression of thioredoxin-1 in the ASJ neuron corresponds with and enhances intrinsic regenerative capacity under lesion conditioning in C. elegans. FEBS Lett. 597, 1880-1893.
  • Wang, Y.L., Grooms, N.W.F., Jaklitsch, E.L., Schulting, L.G., and Chung, S.H. (2023). High-throughput submicron-resolution microscopy of Caenorhabditis elegans populations under strong immobilization by cooling cultivation plates. iScience 26, 105999.
  • Wang, Y.L., Grooms, N.W.F., Ma, C.W., and Chung, S.H. (2023). Assembly and Operation of a Cooling Stage to Immobilize C. elegans on Their Culture Plates. J Vis Exp 195, e65267. 10.3791/65267.
  • Wang, Yao L., Grooms, Noa W. F., Civale, Sabrina C., Chung, Samuel H. (2021). Confocal imaging capacity on a widefield microscope using a spatial light modulator. PLoS ONE, 16(2),e0244034. 10.1371/JOURNAL.PONE.0244034
  • M.B. Harreguy, V. Marfil, N.W. F. Grooms, C.V. Gabel, S.H. Chung, G. Haspel, Ytterbium-Doped Fibre Femtosecond Laser Offers Robust Operation with Deep and Precise Microsurgery of elegans Neurons, Scientific Reports, 10, 2020 4545
  • H. Cai, Y.L. Wang, R.T. Wainner, N.V. Iftimia, C.V. Gabel, S.H. Chung, Wedge Prism Approach for Simultaneous Multichannel Microscopy, Scientific Reports, 9, 2019, 17795
  • S.H. Chung, M.R. Awal, J. Shay, M.M. McLoed, E. Mazur, C.V. Gabel, Novel DLK-Independent Neuronal Regeneration in Caenorhabditis Elegans Shares Links with Activity- Dependent Ectopic Outgrowth, Proceedings of the National Academy of Sciences, 113, 2016, E2852-E2860

Faculty

Sep 15, 2023

Announcing Fall 2023 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Fall 2023 PEAK Experiences Awards. Projects this fall are tackling a range of topics and modes with students developing an autobiographical zine, studying the development of amphibian limbs, building better rocket parts, and more. BASE CAMP AWARDS Farhad Ibrahimzade COE’26 & […]

Undergraduate

May 18, 2022

Announcing Summer 2022 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Summer 2022 PEAK Experiences Awards.

Undergraduate

Oct 12, 2021

Announcing Fall 2021 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Fall 2021 PEAK Experiences Awards. The PEAK Experiences Awards are a progressively structured sequence of opportunities designed to support learners as they continue climbing to new heights of achievement in undergraduate research and creative endeavor throughout their Northeastern journeys. ASCENT AWARDS […]

Faculty

Apr 09, 2019

FY20 TIER 1 Award Recipients

25 COE faculty and affiliates were recipients of FY20 TIER 1 Interdisciplinary Research Seed Grants for 18 different projects representing up to $900K dollars of investment in research.

Faculty

Oct 25, 2017

Insights into Nerve Regeneration

BioE Assistant Professor Samuel Chung is studying microscopic worms to gain insights into nerve regeneration with hopes to help people with spinal cord injuries. Source: News @ Northeastern Samuel Chung is motivated by the “flash of insight”—that moment when days upon days of research result in a key breakthrough or discovery. He’s already encountered a […]

Faculty

Sep 01, 2017

New Faculty Spotlight: Samuel Chung

Samuel Chung joins the Bioengineering department in September 2017 as an Assistant Professor.

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