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Heather Clark

Professor, Bioengineering
Interdisciplinary with, Chemistry and Chemical Biology
Affiliated Faculty, Chemical Engineering
271 The Fenway
360 Huntington Avenue
Boston, MA 02115


Ph.D. Analytical Chemistry, University of Michigan, 1999
B.S. Chemistry, University of Michigan

Research & Scholarship Interests

Optical nanosensors for biological analysis
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • Young Faculty Award, Defense Advanced Research Projects Agency

Selected Publications

  • G. Rong, S. Corrie, H.A. Clark, In Vivo Biosensing: Progress and Perspectives, ACS Sensors, 2(3), 2017, 327-338
  • T.T. Ruckh, C.G. Skipwith, W. Chang, A.W. Senko, V. Bulovic, P. Anikeeva, H.A. Clark, Ion-Switchable FRET Rates in Ratiometric Nanocrystal Potassium Sensors, ACS Nano, 10(4), 2016, 4020-4030
  • W. Di, R.S. Czarny, N.A. Fletcher, M.D. Krebs, H.A. Clark, Comparative Study of Poly(epsilon-caprolactone) and Poly(Lactic-co-Glycolic Acid)-Based Nanofiber Scaffolds for  pH-Sensing, Pharmaceutical Research, 2016
  • A. Sahari, T.T. Ruckh, R. Hutchings, H.A. Clark, Development of an Ultra-Selective Optical Nanosensor for Potassium Imaging, Analytical Chemistry, 87(21), 2015, 10684-10687
  • R.P. Walsh, J. Morales, C.G. Skipwith, T.T. Ruckh, H.A. Clark, Enzyme Linked DNA Dendrimers for the Detection of Acetylcholine, Nature Scientific Reports, 2015
  • J.M. Morales, C.G. Skipwith, H.A. Clark, Quadruplex Integrated DNA (QuID) Nanosensors for Monitoring Dopamine, Sensors, 15(8), 2015, 19912-19924
  • K.J. Cash, C. Li, L.V. Wang, H.A. Clark, Photoacoustic Imaging of Nanosensors for Therapeutic Drugs, In Vivo, ACS Nano, 9(2), 2015, 1692-1698
  • M.K. Balaconis, Y. Luo, H.A. Clark, Glucose-Sensitive Nanofiber Scaffolds Prevent Sensor Diffusion, In Vivo, Analyst, 140, 2015, 716-723 *selected as a HOT article

Related News

October 12, 2018

BioE/COS Professor Heather Clark directs the new Systems Bioanalysis and Chemical Imaging Institute which will focus on finding ways to image the chemistry of our bodies.

February 6, 2018

Bioengineering Professor Heather Clark and Associate Professor Mark Niedre awarded a $1.4M, 4-year NIH grant to develop circulating red blood cell based nanosensors for non-invasive optical drug monitoring.

September 1, 2017

Heather Clark joins the Bioengineering department in September 2017 as a Professor with a joint appointment in Chemistry and Chemical Biology.