Guohao Dai

Professor,  Bioengineering

Contact

Social Media

Office

  • 224 ISEC
  • 617.373.2207

Research Focus

3-D bioprinting technology, stem cells technology and vascular bioengineering

Education

  • Post-doc, Vascular Biology, Harvard Medical School
  • Ph.D, Biomedical Engineering, Massachusetts Institute of Technology
  • M.S, Biomechanics, Peking University
  • B.S, Mechanical Engineering, Peking University

Honors & Awards

  • 2012 National Scientist Development Award, American Heart Association
  • 2014 NSF Career Award
  • 2015 Rising Star Award, Biomedical Engineering Society Cellular and Molecular Bioengineering
  • 2015 The Institute’s James M. Tien ’66 Faculty Early Career Award, Rensselaer Polytechnic Institute
  • 2018 College of Engineering Faculty Fellow
  • 2018 Fellow American Heart Association
  • 2022-2025 Biomedical Engineering Society (BMES) Board of Directors
  • 2023 American Institute for Medical and Biological Engineering (AIMBE) Fellow

Professional Affiliations

  • American Heart Association, Fellow
  • Biomedical Engineering Society
  • North American Vascular Biology Organization

Research Overview

3-D bioprinting technology, stem cells technology and vascular bioengineering

Selected Research Projects

  • Bioengineer Long-lasting 3D Neurovascular Microphysiological System to Model Chronic Inflammation-mediated Neurodegeneration
    • – Principal Investigator, NASA
  • CAREER: Engineer a Functional 3-D Vascular Niche to Support Neural Stem Cell Self-Renewal
    • – Principal Investigator, National Science Foundation
  • Differentiation Arterial and Venous Endothelial Cells from Embryonic Stem Cells
    • – Principal Investigator, National Institutes of Health
  • Elastic Printable Biomaterials for 3-D Bioprinting of Vascular Conduit
    • – Principal Investigator, National Institutes of Health
  • Transcriptional Regulation of Arterial Venous Differentiation
    • – Principal Investigator, American Heart Association

Selected Publications

  • Baltazar, Tânia, Merola, Jonathan, Catarino, Carolina, Xie, Catherine B., Kirkiles-Smith, Nancy C., Lee, Vivian, Hotta, Stephanie, Dai, Guohao, Xu, Xiaowei, Ferreira, Frederico C., Saltzman, W. Mark, Pober, Jordan S., Karande, Pankaj (2020). Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells. Tissue Engineering, 26(5-6),227-238. 10.1089/TEN.TEA.2019.0201
  • M.S. Ozturk, V.K. Lee, H. Zou, R.H. Friedel, X.Intes, G.Dai High Resolution Tomographic Analysis of in vitro 3D Glioblastoma Tumor Model under Long-Term Drug Treatment, Science Advances, 6(10), 2020, 7513
  • W. Song, A. Chiu, L.-H. Wang, R.E. Schwartz, B. Li, N. Bouklas, D.T. Bowers, V.K. Lee, G. Dai, M. Ma, et al. Engineering Transferrable Microvascular Meshes for Subcutaneous Islet Transplantation, Nature Communications, 10, 2019, 4602
  • L. Niklason, G. Dai, Arterial Venous Differentiation for Vascular Bioengineering, Annual Review of Biomedical Engineering, 2018, 4(20), 431-447
  • C. Xu, W. Lee, G. Dai, Y. Hong, Highly Elastic Biodegradable Single-Network Hydrogel for Cell Printing, ACS Applied Materials & Interfaces, 10(12), 2018, 9969-9979
  • T.B. Dorsey, D. Kim, A. Grath, D. James, G. Dai Multivalent Biomaterial Platform to Control the Distinct Arterial Venous Differentiation of Pluripotent Stem Cells, Biomaterials, 2018, 185, 1-12

Faculty

Feb 02, 2024

Developing Biodegradable Elastic Hydrogels for 3D Tissue Engineering

BioE Professor Guohao Dai was awarded a patent for “Biodegradable elastic hydrogels for bioprinting.”

Faculty

Dec 07, 2023

2023 Stanford University Annual Assessment of Author Citations

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes those […]

Faculty

Mar 28, 2023

Dai and Huang-Saad Named AIMBE Fellows

BioE Associate Professors Guohao Dai and Aileen Huang-Saad were inducted into the American Institute for Medical and Biological Engineering (AIMBE) Fellows Class of 2023. Dai was elected “for contributions in vascular mechanobiology and 3D bioprinting vascular networks for tissue engineering, regenerative medicine applications” and Huang-Saad was elected “for outstanding contributions to the development of BME entrepreneurship education microenvironments and studying their impact on the engagement of diverse populations.”

Faculty

Nov 02, 2022

2022 Stanford University Annual Assessment of Author Citations

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

Faculty

Aug 10, 2022

Dai Selected for BMES Board of Directors

BioE Associate Professor Guohao Dai was selected to be on the Biomedical Engineering Society (BMES) Board of Directors. He will assume the position after the annual meeting in October.

Undergraduate

May 18, 2022

Announcing Summer 2022 PEAK Experiences Awardees

Several engineering students and science students mentored by COE faculty are recipients of Northeastern’s Summer 2022 PEAK Experiences Awards.

Faculty

Apr 21, 2022

DoD Discovery Award to Develop Human Vascular Malformation Model From iPSCs

BioE Associate Professor Guohao Dai received a $314K Discovery Award from the Department of Defense for “Human iPSCs derived 3D perfused model of vascular malformation”.

Guohao Dai, Abby Koppes, Ryan Koppes

Faculty

Apr 04, 2022

$2M NASA Grant To Build Long Lasting Neurovascular Model

BioE Associate Professor Guohao Dai, ChE Associate Professor Abigail Koppes, and ChE Assistant Professor Ryan Koppes received a $2M grant from NASA titled “Bioengineer Long-lasting 3D Neurovascular Microphysiological System to Model Chronic Inflammation-mediated Neurodegeneration”.

Faculty

Dec 23, 2021

COE Professors Selected in Stanford University List of Top 2% Scientists Worldwide

The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2 percent of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes […]

guohao dai, ryan koppes, & abigail koppes

Faculty

May 20, 2021

Improving Vein Grafts for Patients with Cardiovascular Diseases

BioE Associate Professor Guohao Dai (PI), ChE Assistant Professors Ryan Koppes (PI), and Abigail Koppes (co-PI) were awarded a $430K NIH grant from the National Institute of Neurological Disorders and Stroke for “Bioengineer a Humanized Autonomic Neurovascular Innervation on a Chip”.

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