You are here

k.lewis@northeastern.edu

Profile

Kim Lewis

Professor, Biology
Affiliated Faculty, Bioengineering
617.373.8238
306C Mugar Life Sciences
360 Huntington Avenue
Boston, MA 02115

Biography

The focus of my research is on antimicrobial drug tolerance and drug discovery. Microorganisms produce persister cells, which are dormant variants that are highly tolerant to killing by all known antibiotics. Persisters are largely responsible for relapsing chronic infections caused by biofilms. Using transcriptome analysis, cell sorting and whole genome sequencing we are identifying genes responsible for persister formation. Both drug tolerance and conventional drug resistance require development of new antibiotics, and our discovery efforts include screening compounds from previously “uncultured” species of microorganisms, and high-throughput screening for compounds with novel mode of action.

Education

Ph.D., Biochemistry, Moscow University, Moscow, USSR
B.Sc., Biology, Moscow University, Moscow, USSR

Research & Scholarship Interests

Molecular Microbiology
Affiliated With

Department Research Areas

College Research Initiatives

Related News

March 23, 2017

21 COE faculty and affiliates were recipients of FY18 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing $600K dollars of investment in research.