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Mark Niedre

Associate Professor and Associate Chair For Research, Bioengineering
217 ISEC
360 Huntington Avenue
Boston, MA 02115


Post-Doctoral Fellowship: Harvard Medical School and Massachusetts General Hospital, 2005-2008 Ph.D., Medical Biophysics, University of Toronto, 2005 B.Eng., Engineering Physics, McMaster University, 1998


  • PhD, University of Toronto, 2004

Research & Scholarship Interests

Biomedical optics and non-invasive imaging, rare cell detection and tracking in the body, ultrafast time-domain diffuse optical imaging, image reconstruction and biomedical signal processing.
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • 2015 COE Faculty Fellow
  • 2015 Søren Buus Outstanding Research Award
  • Massachusetts Life Sciences Center New Investigator Award

Selected Publications

  • V. Pera, X. Tan, J. Runnels, N. Sardesai, C.P. Lin, M. Niedre, Diffuse Fluorescence Fiber Probe for In Vivo Detection of Circulating Cells, Journal of Biomedical Optics, 22(3),          2017, 037004
  • Y. Mu, V. Pera, M. Niedre, Multiplexed Fluorescence Mediated Tomography with Temporal and Spectral Data, Journal of Biomedical Optics, 21(10),       2016, 105001
  • S. Markovic, S. Li, M. Niedre, Performance of Computer Vision In Vivo Flow Cytometry with Low Fluorescence Contrast, Journal of Biomedical Optics, 20(3), 2015, 35005
  • V. Pera, D.H. Brooks, M. Niedre, On the use of Cramer-Rao Bounds in diffuse optical Tomography, Journal of Biomedical Optics, 19(2), 2014, 025002
  • S. Markovic, B. Li, V. Pera, M. Sznaier, O. Camps, M. Niedre, A Computer Vision Approach to RareCell In Vivo Flow Cytometry, Cytometry A, 83A, 2013, 1113-1123
  • N. Pestana, L. Mortensen, J. Runnels, M. Niedre, et al., An Improved Prototype Diffuse Fluorescence Flow Cytometer for High Sensitivity Detection of Rare Circulating Cells In Vivo, Journal of Biomedical Optics, 18(7), 2013, 77002
  • Y. Mu, N. Valim, M. Niedre, Evaluation of a Fast Single-photon Avalanche Photodiode for Measurement of Early Transmitted Photons Through Diffusive Media, Optics Letters, 38(12), 2013, 2098-2100
  • N. Valim, J. Brock, M. Leeser, M. Niedre, The Effect of Temporal Impulse Response on Experimental Reduction of Photon Scatter in Time-Resolved Diffuse Optical Tomography, Physics in Medicine and Biology, 58(2), 2013, 335-349
See Google Scholar Profile for all publications »

Related News

May 17, 2018

BioE Associate Professor Mark Niedre and ECE alum Eric Zettergren, ME'11, were awarded a patent for "Systems and methods for sensing, enumerating and imaging rare cells with diffuse light".

February 6, 2018

Bioengineering Professor Heather Clark and Associate Professor Mark Niedre awarded a $1.4M, 4-year NIH grant to develop circulating red blood cell based nanosensors for non-invasive optical drug monitoring.

March 23, 2017

21 COE faculty and affiliates were recipients of FY18 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing $600K dollars of investment in research.

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