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z.zhou@northeastern.edu

Profile

Sunny Zhou

424 Hurtig Hall
360 Huntington Avenue
Boston, MA 02115

Education

1997 Ph.D., The Scripps Research Institute
1990 B.Sc., Peking University, Beijing, China

Research & Scholarship Interests

Analytical, bioorganic, medicinal, and protein chemistry
Affiliated With

Department Research Areas

Selected Publications

  • W. Qu, K.C. Catcott, K. Zhang, S. Liu, J.J. Guo, J. Ma, M. Pablo, J. Glick, Y. Xiu, N. Kenton, X. Ma, R.I. Duclos, Z.S. Zhou, Capturing Unknown Substrates via in Situ Formation of Tightly Bound Bisubstrate Adducts: S-Adenosyl-Vinthionine as a Functional Probe for AdoMet-Dependent Methyltransferases, Journal of the American Chemical Society, 138(9), 2016, 2877-2880
  • S. Liu, K.R. Moulton, J.R. Auclair, Z.S. Zhou, Mildly Acidic Conditions Eliminate Deamidation Artifact During Proteolysis: Digestion with Endoprotease Glu-C at pH 4.5, Amino Acids, 48(4), 2016, 1059-67
  • C. Chumsae, P. Hossler, H. Raharimampionona, Y. Zhou, S. McDermott, C. Racicot, C. Radziejewski, Z.S. Zhou, When Good Intentions Go Awry: Modification of a Recombinant Monoclonal Antibody in Chemically Defined Cell Culture by Xylosone, an Oxidative Product of Ascorbic Acid, Analytical Chemistry, 87(15), 2015, 7529-7534
  • R.I. Duclos Jr., D.C. Cleary, K.C. Catcott, Z.S. Zhou, Synthesis and Characterization of Se-adenosyl-L-Selenohomocysteine Selenoxide, Journal of Sulfur Chemistry, 36(2), 2015, 135-144
  • C. Chumsae, L.L. Zhou, Y. Shen, J. Wohlgemuth, E. Fung, R.Burton, C.H. Radziejewski, Z.S. Zhou, Discovery of a Chemical Modification by Citric Acid in a   Recombinant Monoclonal Antibody, Analytical Chemistry 86(18), 2014, 8932-8936
  • J.J. Klaene, W. Ni, J.F. Alfaro, Z.S. Zhou, Detection and Quantitation of Succinimide in Intact Protein via Hydrazine Trapping and Chemical Derivatization, Journal of Pharmaceutical Sciences, 103(10), 2014, 3033-3042
  • M. Liu, Z. Zhang, J. Cheetham, D. Ren, Z.S. Zhou, Discovery and Characterization of a Novel Photo-Oxidative Histidine-Histidine Crosslink in IgG1 Antibody Utilizing 18O-labeling and Mass Spectrometry, Analytical Chemistry, 86(10), 2014, 4940-4948
  • N.W. Hodgson, M.I. Waly, Y.M. Al-Farsi, M.M. Al-Sharbati, O. Al-Farsi, A. Ali, A. Ouhtit, T. Zang, Z.S. Zhou, R.C. Deth, Decreased Glutathione and Elevated Hair Mercury Levels are Associated with Nutritional Deficiency-Based Autism in Oman, Experimental Biology and Medicine, 239(6), 2014, 697-706

Related News

March 23, 2017

21 COE faculty and affiliates were recipients of FY18 TIER 1 Interdisciplinary Research Seed Grants for 12 different projects representing $600K dollars of investment in research.

February 1, 2017

BioE Assistant Professor Ambika Bajpayee (PI) and MIE/BioE Associate Professor Sandra Shefelbine (Collaborator) awarded a $310K DOD Peer Reviewed Medical Research Program Discovery Award